The Conservatives have lost the North Shropshire by-election, a shock result that has dealt Boris Johnson another significant blow to his premiership.

After a bruising few weeks in Westminster, the voters of North Shropshire delivered their own body blow on Boris Johnson, booting the Tories out of a seat they've never lost on the second biggest swing by-election since 1945.

A 27-year-old woman has been arrested on suspicion of child neglect after four children - two sets of twin boys aged three and four - died in a house fire in south London.

Scientists have discovered a millipede with 1,306 legs - the most of any known animal - and say it is a "marvel of evolution".

At least 27 people are feared dead after a fire tore through a psychiatric clinic in the Japanese city of Osaka.

Wales will introduce new social distancing restrictions and close nightclubs from 27 December in a bid to slow the spread of the Omicron coronavirus variant.

A search warrant has been issued for Alec Baldwin's phone after the fatal shooting of a cinematographer, an American court has said.

Sex And The City star Chris Noth has said allegations of sexual assault made against him by two different women are "categorically false", as fitness brand Peloton pauses its latest advertising campaign featuring the star.

Partial human remains found nearly 40 years ago in a bin bag have been confirmed as those of Frank Little Jr - a former songwriter and guitarist for R&B group The O'Jays.